Terumo Cardiovascular Group

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Perfusion Circuits

Information provided on this website is not intended to make claims that the products are safe and effective for any use other than those explicitly described in the Instructions for Use. Clinicians should refer to the Instructions for Use or Owner's Manuals for complete information on the intended use of any product mentioned in this website.

CASE STUDY: High Flow, Low Prime Oxygenator Contributes to Blood Management Program
Jeffrey Wilson, CCP, describes how the perfusion team at St. Joseph Hospital Center achieved a significant reduction in prime volume using CAPIOX RX Oxygenators and blood management strategies.

CASE STUDY: Bloodless Cardiac Surgery is a Team Sport
Ninety percent of patients weighing over 25 kilos have surgery without receiving blood at The Heart Center at Nationwide Children's Hospital in Columbus, Ohio. Read about its blood management program.

STANDARDS: Recommendations for Standards of Monitoring during Cardiopulmonary Bypass
Clinical associations representing surgeons, perfusionists and anaesthetists in Great Britain list "continuous in-line monitoring as a minimal standard of monitoring required during cardiopulmonary bypass."

STUDY: Children's Hospital Studies New Oxygenator with Integrated Arterial Filter
Joseph Deptula, CCP, Children's Hospital, found that the CAPIOX FX05 Oxygenator significantly reduced CPB prime volumes and surface area while reducing blood donor exposure; all without compromising patient safety.

CASE STUDY: Pediatric Blood Management Program Optimal With 3-Year-Olds
Medical College of Georgia Health Children's Medical Center uses smaller tubing and oxygenator to eliminate 200 ml of prime volume to benefit three-year-old patients.

CASE STUDY: Bloodless Surgery for Pediatric Cardiac Surgery Patients
Dave Fitzgerald, CCP, describes how the INOVA Fairfax Hospital team has adopted Jehovahs Witnesses blood management strategies for all patients- adults and pediatric.

SYNOPSIS: European Team Outlines Benefits Of Minimized Perfusion Circuit
At the Optimizing Cardiac Surgery Symposium on March 5, 2010, Uwe Schonrock, CCP, Klinikum Braunschweig, shared the clinical benefits of his team's use of the ROCSafe Hybrid Perfusion System in 2,500 cases.

CD-ROM: CSI Perfusion: Discovering the Evidence for Effective Blood Management
David Fitzgerald, CCP, shares results from the blood management program at Inova Heart and Vascular Institute at the Optimizing Cardiac Surgery Symposium in Orlando in May 2009.

CLINICAL STUDY: Prescriptive Patient Extracorporeal Circuit and Oxygenator Sizing Reduces Hemodilution and Allogeneic Blood Product Transfusion during Adult Cardiac Surgery. JECT. 2013; 45:167-172. Bronson S, et al. (PDF)

ABSTRACT: Bloodless Cardiac Surgery and the Pediatric Patient: A Case Study. Perfusion 2008; 23: 131-134. Ging, AL et al.
The authors present blood management strategies in which a 5.9 kg Jehovah's Witness patient underwent successful correction of a VSD without the use of transfusions.

ABSTRACT: Beneficial Effects of Modern Perfusion Concepts in Aortic Valve and Aortic Root Surgery. Perfusion 2009;24: 37-44, Kutschka, et al.
In this 170-patient study, the use of the ROCSafe™ Hybrid Perfusion System was found to reduce side effects of standard extracorporeal circulation.

ABSTRACT: Summary of Select Studies on Air Bubble Removal
Several studies indicate that gaseous microemboli in the extracorporeal circuit is a clinical concern; some demonstrate an association between GME and neurological damage or other organ failure after cardiac surgery.

ABSTRACT: A New Minimized Perfusion Circuit Provides Highly Effective Ultrasound Controlled Deairing. Artificial Organs. 2007 Mar; 31(3):215-220, Kutschka, et al.
This study compared a ROCSafe™ Hybrid Perfusion System to conventional perfusion circuit and results indicated that active venous deairing was significantly reduced compared to passive deairing on a conventional circuit.

ABSTRACT: Investigation of Blood Compatibility of PMEA-Coated Extracorporeal Circuits. Journal of Bioactive and Compatible Polymers, Vol 17, Sept 2002. Kocakulak M, et al.
In a study comparing PMEA-coated and uncoated oxygenators, the authors found greater retention of clotting factors and platelets and less post-op hemorrhaging when using PMEA-coated oxygenators.

ABSTRACT: Emerging Technologies in Biocompatible Surface Modifying Additives: Quest for Physiologic CPB. Cardiovascular and Hematological Agents. 2004; Vol. 2:No 4. Gunaydin S, et al.
The authors compare surface coatings, including Xcoating, in 155 CPB cases for chemical composition, biomaterial evaluation and clinical efficacy.

ABSTRACT: The CAPIOX RX05 Oxygenator: Pediatric Clinical Observations. Perfusion. 2003;18, 321-323, Tinius, et al.
The authors provide clinical observations on the use of the CAPIOX® BABY RX™ Oxygenator and reducing prime volume in neonate circuits.

ABSTRACT: Biocompatibility of Poly (2-methoxyethylacrylate) Coating for Cardiopulmonary Bypass. Annals Thoracic Cardiovascular Surgery, 2003, Volume 9, No 1. Noguchi, et al.
The authors compare the biocompatibility of PMEA-coated and heparin-coated circuits by measuring several inflammatory markers. Results indicate PMEA-coated circuits are as biocompatible as heparin coated circuits.

ABSTRACT: Xcoating: A New Biopassive Polymer Coating. Canadian Perfusion Canadienne, Volume 11, No 2, June 2001. Schiel, et al.
This paper explains the mechanism and benefits of Xcoating.

ANIMATION: Prescriptive Oxygenation 3-D Animation
This animation illustrates how Terumo's unique oxygenators, packaging solutions and brackets make implementing Prescriptive Oxygenation quick and convenient.